Amlodipine
Calcium channel blocker (dihydropyridine) · Cardiovascular
Indications
- Hypertension
- Stable angina
- Vasospastic angina
Dosing
- Adult
- 5 mg OD, max 10 mg OD
- Paediatric
- 6–17 years: 2.5–5 mg OD
Routes
- Oral
Contraindications
- Cardiogenic shock
- Unstable angina (excluding vasospastic)
- Significant aortic stenosis
Side effects
- Peripheral oedema (ankle)
- Flushing
- Headache
- Palpitations
Monitoring
- BP monitoring
- Ankle oedema assessment
Key interactions
- Simvastatin (max 20 mg simvastatin if combined)
- CYP3A4 inhibitors (increase levels)
Reviewed by DocBuddy Clinical Team on . Written as a study aid for medical students. Always check a current local formulary before prescribing.
Practise the pharmacology
Questions on Amlodipine and the rest of cardiovascular pharmacology are in the app, with the drug cards a tap away while you answer.