Amoxicillin

Penicillin antibiotic · Infectious Disease

Indications

  • Community-acquired pneumonia
  • Urinary tract infection
  • H. pylori eradication
  • Otitis media
  • Sinusitis

Dosing

Adult
500 mg–1 g TDS; severe: 1 g TDS
Paediatric
< 10 years: 250 mg TDS (mild); 500 mg TDS (severe)

Routes

  • Oral
  • IV
  • IM

Contraindications

  • Penicillin allergy
  • Infectious mononucleosis (rash risk)

Side effects

  • Diarrhoea
  • Nausea
  • Rash
  • Anaphylaxis (rare)

Monitoring

  • Allergy history before first dose

Key interactions

  • Methotrexate (reduced excretion)
  • Warfarin (INR monitoring)

Reviewed by DocBuddy Clinical Team on . Written as a study aid for medical students. Always check a current local formulary before prescribing.

Practise the pharmacology

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